The following schools are hosting Apply Missouri events for the 2020-21 school year:
- Bayless High School
- Belton High School
- Bolivar High School
- Boonville High School
- Campbell High School
- Central High School
- Central High School (Kansas City)
- Central High School (Springfield)
- Clyde C. Miller Career Academy
- Confluence Prep Academy
- Conway High School
- Crane High School
- David H Hickman High School
- Dixon High School
- East High School/KCPS
- Everton High School
- Fair Play High School
- Festus Senior High School
- Fort Osage High School
- Gateway Science Academy
- Gateway STEM High School
- Hancock Place High School
- Harrisonville High School
- Hazelwood East High School
- Hazelwood Opportunity Center
- Iberia High School
- Jefferson High School
- Jennings High School
- Kansas City School district
- Kickapoo High School
- KIPP St. Louis High School
- Kirksville High School
- Lafayette High School
- Laquey High School
- Liberty High School
- Lincoln R-II High School
- Louisiana High School
- Maplewood Richmond Heights High School
- Mark Twain High School
- Marshfield High School
- McCluer North High School
- Meadow Heights High School
- Monett High School
- Monroe City R-1 High School
- New Franklin R-1 High School
- North County High School
- North Kansas City High School
- Northeast High School
- Northwest Academy of Law
- Notre Dame High School
- Odessa High School
- Osage Co R-1 High School
- Osceola High School
- Parkview High School
- Paseo Academy
- Pattonville High School
- Raytown High School
- Raytown South High School
- Reeds Spring High School
- Ritenour High School
- Rock Bridge High School
- Salem High School
- Salisbury R-IV High School
- Santa Fe R-X High School
- Sheldon High School
- Sikeston Senior High School
- Sullivan High School
- Sumner High School
- Theodore Roosevelt High School
- Timberland High School
- Twin Rivers High School
- Van Horn High School
- Vashon High School
- Viburnum High School
- Warrensburg High School
- William Chrisman High School